Aidan Finn has a great blogpost that can help some folks remedy installation issues with Windows Intune! Note as per the blog post, after i configured WPAD my connectivity issues had gone away.

http://www.aidanfinn.com/?p=12073
Note to configure Option 252 on a Microsoft DHCP Server you will need to follow this guide:

http://technet.microsoft.com/en-us/library/bb794881.aspx